The cases included people eating meat since March 1, it said, but no supplier, distributor or brand of meat has been identified.
"Traceback investigations continue to identify the source of raw beef given at grocery stores and restaurant locations where people are being ill with eating," the CDC said.
The diseases that began on March 1, and the infected age at the age of 1 to 83 years, with a median age of 19, said.
"Diseases that occur after March 26 may not be reported due to the time that occurs between a person who is sick with E. coli and when the disease is reported. It takes an average of two to three week, "said the CDC.
Symptoms include severe abdominal pain, diarrhea and vomiting. They begin, on average, three to four days after the bacteria stick. Most people get 5 to 7 days. The first reported symptoms from this outbreak began on March 2.
Buyers are encouraged to prevent the spread of E. coli by washing hands, cooking beef in an internal temperature of 160 degrees and keeping foods that are not eaten from raw meat to prevent high-quality salts.