Online pharmacy Valisure has discovered another chemical that causes cancer in blood pressure produced by companies including Novartis, according to a US Food and Drug Administration petition.
FDA filing on Thursday involves dimethylformamide, or DMF, a solvent found in valsartan in the heart of the drug, according to Valisure. New Haven, Connecticut-based pharmacy operation requested that the FDA lower how much DMF is allowed in drugs and to remember the valsartan referred to to handle the high level of DMF.
since last year, when the chemical N-Nitrosodimethylamine, or NDMA, was found in a summary version of valsartan, as a drug used for decades treatment of hypertension.
The FDA reported in March the impurities found inof chemical reactions that occur in the drug-producing process or from re-use of materials, such as solvents.
will examine the findings of Valisure, agency spokeswoman at CBS MoneyWatch said. Consumers should continue to take their blood pressure pressure even if it is recalled until they can consult their physicians, according to the regulatory agency.
"The risk associated with sudden abolition of the use of essential medicines far outweighs the risk that our scientists have rated attributed to the continuation of the drug until the patient's doctor or pharmacist provides a safe replacement or other treatment options, "according to the FDA spokesperson.
The World Health Organization has classified DMF as cancer-causing cancer last year.
The FDA does not usually review pharmacists, relying on manufacturers to make sure their products are safe and effective.
Novartis, which makes Diovan, a brand-name version of valsartan, says that DMF does not generally use its drugs, and the information from its suppliers indicates they are not doing.
That said, "Novartis can not fully exclude the possibility that DMF traces (within the applicable limits) may be present in the materials of other components of the resources, "the drug spokesman told CBS MoneyWatch.